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Escin

Article No.: 89871

Escin

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Chemical-physical Data

CAS Number

6805-41-0

Substance Class

Subclass 1

Subclass 2

Specifications and Notes

Certification Scope

Escin reference substance is a primary reference standard with certified absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities).

Certificate of Analysis

Storage Conditions

15-25 °C

Delivery Time

usually a stock item

Special Notes

Escin reference substance is a mixture of structurally related saponins. The assay is determined using various methods. In addition to the total saponin content (determined via a mass balance taking the chromatographic purity into account), also the content calculated as protoescigenin (based on Ph. Eur. Chapters 1829 and 1830 using protoescigenin, Phyproof® article 83898 as standard) is shown on the CoA. The assay methods as well as the specifications in DAB, EP and USP are or were different. Depending on the assay method, a different absolute purity of this reference substance has to be taken into account, as the assay methods are based on different non-related principles. Please note, that PhytoLab also offers protoescigenin as a reference substance (Phyproof® article 83898). The specifications for horse chestnut and horse chestnut extract in the European Pharmacopoeia are related to protoescigenin. The use of a protoescigenin reference standard would thus also allow the determination of the content of escin, calculated as protoescigenin.

Safety and Transport

GHS Symbols

GHS07GHS09

Hazard Statements

H302+H332,H319,H335,H411

Precautionary Statements

P261a, P273, P280b, P305+P338+P351, P312a, P501a

Dangerous Goods

yes

Safety Data Sheet

Transport Conditions

ambient conditions

Customs Tariff Code

29389090

Commodity Description

natural glycoside

Occurrence

Occurrence (botanical genus)

Aesculus sp.

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